One fateful night, Brad Majors and his fiancé, Janet Weiss – a well-behaved, utterly normal couple in love – set out to visit an old professor. A storm and a flat-tire force them to seek help at the castle of Dr. Frank ‘N Furter, an alien, transvestite scientist with a manic genius and insatiable libido. Brad, Janet, and Frank ‘N Furter’s cohorts are swept up into the scientists’ latest experiment. Their misadventures will cause Brad and Janet to question everything they know about themselves, each other, love, and lust.